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Yellow Card reporting — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyYellow Card reportingGPhC CRA

A 36-year-old woman develops angioedema within hours of starting a newly prescribed ACE inhibitor. She needed emergency department treatment and has now recovered. The pharmacist confirms no previous ACE inhibitor exposure. What is the most appropriate action?

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Correct answer: C — Submit a Yellow Card report and advise avoidance pending prescriber review

Serious suspected adverse drug reactions should be reported through the Yellow Card scheme. Angioedema with an ACE inhibitor is clinically important and should be documented clearly to avoid re-exposure. Rechallenge is inappropriate because recurrence can be severe. The prescriber should review future antihypertensive choice.

Reference: MHRA Yellow Card; BNF ACE inhibitors