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Fluconazole in pregnancy — GPhC CRA MCQ

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HardInfectionsFluconazole in pregnancyGPhC CRA

A 30-year-old woman who is 10 weeks pregnant asks to buy oral fluconazole 150mg for vaginal thrush. She has vulval itching and discharge but no pelvic pain, fever or urinary symptoms. She used oral fluconazole before pregnancy. What is the most appropriate alternative?

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Correct answer: DRefer for a pregnancy-appropriate topical imidazole option

Oral fluconazole is generally avoided in pregnancy, and topical imidazole therapy is usually preferred after appropriate assessment. The patient should be referred for pregnancy-safe management. Recurrent or atypical symptoms would also require review. Douching is not recommended and may worsen irritation.

Reference: BNF Fluconazole; NICE CKS Candida - female genital