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Isotretinoin pregnancy prevention — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyIsotretinoin pregnancy preventionGPhC CRA

A 24-year-old woman presents a private prescription for isotretinoin. The prescription is dated 10 days ago and requests 60 days' treatment. She says her pregnancy test was negative before the dermatology appointment and she wants the full quantity before travelling. What is the legal classification/requirement?

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Correct answer: B — Supply must follow isotretinoin pregnancy prevention dispensing restrictions

Isotretinoin is highly teratogenic and has specific Pregnancy Prevention Programme controls, including restrictions on prescription validity and quantity for patients who can become pregnant. A 60-day private supply after 10 days may not comply with those requirements. The pharmacist should check the current rules and contact the prescriber if needed. Leftover isotretinoin must not be used or shared.

Reference: MHRA Isotretinoin safety measures; BNF