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Benzodiazepine dependence — GPhC CRA MCQ

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ModerateCNS TherapeuticsBenzodiazepine dependenceGPhC CRA

A 42-year-old man asks to buy an OTC sleep aid while taking diazepam 10mg at night, obtained from an old prescription. He has used it nightly for 5 weeks and feels anxious when he misses a dose. He drinks alcohol most evenings. What is the most appropriate action?

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Correct answer: A — Advise prescriber review for a supervised gradual reduction plan

Regular benzodiazepine use for several weeks can lead to dependence, and abrupt stopping may cause withdrawal symptoms. Alcohol and sedating antihistamines can worsen sedation and respiratory risk. The safest action is referral for a supervised reduction plan and support for sleep and anxiety. Dose escalation would increase harm.

Reference: BNF; NICE CKS Benzodiazepine and z-drug withdrawal