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Rivaroxaban administration — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsRivaroxaban administrationGPhC CRA

A 67-year-old man with AF collects rivaroxaban 20mg tablets, one to be taken once daily. He says he often takes his medicines first thing before breakfast because he leaves for work early. His eGFR is 66mL/min/1.73m2. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DTake rivaroxaban with food

Rivaroxaban 15mg and 20mg doses should be taken with food to support absorption. Taking it consistently helps reduce missed doses. Splitting tablets or adding extra doses without advice is unsafe. Grapefruit juice is not needed and can complicate counselling around interactions.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment