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Allopurinol during acute gout — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsAllopurinol during acute goutGPhC CRA

A patient prescribed allopurinol 100mg daily for gout prophylaxis develops an acute gout flare 2 weeks later. He asks whether to stop allopurinol during the flare. What would you advise the patient?

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Correct answer: D — Continue allopurinol and seek appropriate treatment for the acute flare

Patients already taking allopurinol should usually continue it during an acute gout flare to avoid urate fluctuations. The acute flare should be treated with an appropriate anti-inflammatory option based on patient factors. Increasing or intermittent use of allopurinol during flares is inappropriate. Aspirin is not preferred for gout pain and can affect urate handling.

Reference: BNF; NICE CKS Gout