Edoxaban dose criteria — GPhC CRA MCQ
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Correct answer: E — Query dose reduction because low body weight and dronedarone affect edoxaban dosing
Edoxaban dosing for non-valvular AF is reduced in patients with low body weight and with certain P-glycoprotein inhibitors such as dronedarone. The prescription should be checked against the relevant criteria and queried if inappropriate. Frequency changes or therapeutic substitutions should not be made by the pharmacist without prescriber involvement. Adding aspirin would increase bleeding risk without routine indication.
Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment