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Valproate original pack dispensing — GPhC CRA MCQ

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HardDispensing and SupplyValproate original pack dispensingGPhC CRA

A patient presents a prescription for sodium valproate 500mg gastro-resistant tablets in plain packaging after the original pack was split for supply. She is of childbearing potential. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Supply in original packaging with patient information and visual pregnancy warnings where possible

Valproate has strict risk minimisation requirements because of teratogenicity and neurodevelopmental harm. Original packs with warnings and patient information should be used where possible, and counselling should reinforce Pregnancy Prevention Programme requirements. Plain repackaging can remove critical safety information. Prior use does not remove the need for ongoing safety communication.

Reference: BNF; MHRA Drug Safety Update; MEP