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Methotrexate labelling safety — GPhC CRA MCQ

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ModerateDispensing and SupplyMethotrexate labelling safetyGPhC CRA

A patient with rheumatoid arthritis is prescribed methotrexate 2.5mg tablets, take six tablets once weekly, and folic acid 5mg once weekly. The label for methotrexate says take six tablets daily. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Stop the dispensing process and correct the methotrexate label before supply

Methotrexate dosing errors can be fatal, and daily labelling for a weekly dose is a serious dispensing error. The supply process should stop until the label is corrected and checked, with clear counselling. Prior familiarity does not make an incorrect label acceptable. Verbal advice cannot compensate for dangerous written directions.

Reference: BNF; MHRA; MEP