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GTN and sildenafil counselling — GPhC CRA MCQ

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ModeratePatient CounsellingGTN and sildenafil counsellingGPhC CRA

A 50-year-old man taking sildenafil for erectile dysfunction asks for advice about new glyceryl trinitrate spray prescribed after exertional chest pain. He used sildenafil last night. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Do not use GTN after recent sildenafil and seek urgent advice if chest pain occurs

Nitrates and phosphodiesterase type 5 inhibitors can cause profound hypotension when combined. The patient should be counselled not to use GTN after recent sildenafil and to seek urgent medical help if chest pain occurs. Using the medicines together while seated does not remove the risk. Exercise advice should be given by the clinical team after angina assessment.

Reference: BNF; NICE CKS Angina