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Time-critical Parkinson's medicines — GPhC CRA MCQ

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ModerateCNS TherapeuticsTime-critical Parkinson's medicinesGPhC CRA

A 57-year-old man with Parkinson's disease is admitted to a care home for respite. His prescription includes co-careldopa 25/100mg five times daily at specific times. The MAR chart gives broad morning, lunch and evening administration windows. What is the most appropriate action?

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Correct answer: CClarify exact administration times because Parkinson's medicines are time critical

Levodopa-containing medicines are time critical; delayed or omitted doses can cause significant worsening of motor symptoms and distress. The care setting should administer at the patient's usual times and document clearly. High-protein meals can reduce levodopa absorption in some patients. Dose or formulation changes should not be made for convenience without prescriber input.

Reference: BNF; NICE CKS Parkinson's disease