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Reconstituted antibiotic expiry — GPhC CRA MCQ

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ModerateDispensing and SupplyReconstituted antibiotic expiryGPhC CRA

A prescription for phenoxymethylpenicillin 250mg/5mL oral solution requires reconstitution. The manufacturer states the reconstituted product expires 7 days after preparation and must be stored in a refrigerator. The label printed by the PMR says use within 28 days. What is the most appropriate action?

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Correct answer: A — Amend the label to the 7-day refrigerated expiry after reconstitution

The patient label must reflect the correct expiry and storage after reconstitution. For many antibiotic liquids, the manufacturer's reconstituted shelf-life is shorter than the PMR default and may require refrigeration. Supplying an inaccurate 28-day expiry risks ineffective or unsafe treatment. The product should normally be reconstituted and labelled appropriately unless local procedures state otherwise.

Reference: BNF; SmPC