Carbamazepine enzyme induction — GPhC CRA MCQ
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Correct answer: E — Carbamazepine may reduce doxycycline exposure through enzyme induction
Carbamazepine is an enzyme inducer and can reduce concentrations of some medicines, including doxycycline, potentially reducing efficacy. This matters for a prolonged acne course where treatment failure is possible. The interaction is not increased doxycycline exposure. The other proposed consequences are not the clinically relevant issue in this case.
Reference: BNF