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Bronchiectasis Pseudomonas eradication — SCE Respiratory MCQ

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HardRespiratory infectionsBronchiectasis Pseudomonas eradicationSCE Respiratory

A 55-year-old woman with bronchiectasis is reviewed after two exacerbations treated with ciprofloxacin. Her latest sputum culture grows Pseudomonas aeruginosa for the first time; she feels back to baseline after antibiotics. HRCT shows stable bronchiectasis and FEV1 is 68% predicted. The team wants to reduce the chance of chronic colonisation. What is the most appropriate management?

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Correct answer: D — Attempt eradication therapy guided by sputum sensitivity

New isolation of Pseudomonas in bronchiectasis should prompt consideration of eradication therapy to prevent chronic infection. Waiting for repeated isolates may miss a window to eradicate. Airway clearance remains part of core management even when symptoms improve.

Reference: BTS Bronchiectasis Guideline 2019