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Aspergilloma — SCE Respiratory MCQ

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ModerateRespiratory infectionsAspergillomaSCE Respiratory

A 61-year-old man with prior cavitating tuberculosis has recurrent haemoptysis. CT shows a mobile intracavitary fungal ball with an air crescent in the right upper lobe. Aspergillus IgG is positive, inflammatory markers are normal and there is no tissue invasion. He is haemodynamically stable after a 100 mL bleed. What is the most likely diagnosis?

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Correct answer: ASimple aspergilloma

A mobile fungal ball in a pre-existing cavity with Aspergillus IgG positivity is a simple aspergilloma. Invasive aspergillosis requires tissue invasion and usually occurs in immunocompromised hosts. Haemoptysis risk drives management discussions, including embolisation for significant bleeding and surgery in selected cases.

Reference: ERS chronic pulmonary aspergillosis guidance; BTS haemoptysis resources