skip to main content

Drug-induced pneumonitis — SCE Respiratory MCQ

Instant feedback + full explanation. One question, done properly.

HardInterstitial lung diseaseDrug-induced pneumonitisSCE Respiratory

A 76-year-old man on amiodarone for atrial fibrillation develops subacute dyspnoea, cough and weight loss. HRCT shows bilateral high-attenuation ground-glass and organising pneumonia-like consolidation. TLCO has fallen from 78% to 46% predicted over a year, and thyroid function is mildly abnormal. Cultures and autoimmune serology are negative. What is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Amiodarone-induced lung disease

Amiodarone can cause pneumonitis with high-attenuation infiltrates due to iodine content and a falling TLCO. Heart failure is plausible in atrial fibrillation, but the imaging pattern, systemic features and negative infection work-up support drug toxicity. Stopping the offending drug and specialist assessment are central.

Reference: BNF; BTS ILD resources