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Obesity hypoventilation overlap — RCPSC IM MCQ

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ModerateRespirologyObesity hypoventilation overlapRCPSC IM

A 73-year-old man with COPD reports morning headaches and daytime somnolence. BMI is 41 kg/m2. Oxygen saturation is 91 percent awake, serum bicarbonate is 34 mmol/L, and spirometry shows moderate obstruction. What is the most appropriate investigation?

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Correct answer: AD-dimer

Obesity, hypersomnolence, elevated bicarbonate, and COPD raise concern for chronic hypercapnia and sleep-disordered breathing. ABG and sleep testing assess obesity hypoventilation and overlap syndrome.

Reference: Canadian Thoracic Society sleep-disordered breathing guidance