A 30-year-old woman has heavy menstrual bleeding, lifelong easy bruising, and excessive bleeding after dental extraction. Platelet count, PT, and

Question

A 30-year-old woman has heavy menstrual bleeding, lifelong easy bruising, and excessive bleeding after dental extraction. Platelet count, PT, and aPTT are normal. Her mother had similar bleeding. What is the most appropriate investigation?

Accepted Answer

von Willebrand factor antigen and activity testing

Answer

Bone marrow biopsy

Answer

Direct antiglobulin test

Answer

Factor V Leiden mutation testing

Answer

JAK2 mutation testing

von Willebrand disease — RCPSC IM MCQ

A 30-year-old woman has heavy menstrual bleeding, lifelong easy bruising, and excessive bleeding after dental extraction. Platelet count, PT, and aPTT are normal. Her mother had similar bleeding. What is the most appropriate investigation?