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Myasthenia gravis with thymoma — RCPSC IM MCQ

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HardNeurologyMyasthenia gravis with thymomaRCPSC IM

A 34-year-old woman has episodic diplopia, ptosis worse in the evening, and chewing fatigue. Examination shows fatigable upward gaze and normal reflexes. Acetylcholine receptor antibodies are positive. CT chest shows a 4 cm anterior mediastinal mass. What is the most appropriate management?

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Correct answer: BPyridostigmine, neurology referral, and thymectomy assessment

Generalized myasthenia gravis with an anterior mediastinal mass suggests thymoma. Symptomatic therapy and specialist referral for thymectomy and immunotherapy planning are appropriate.

Reference: Canadian neurology practice guidance; myasthenia consensus guidance