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Septic shock — RCPSC IM MCQ

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ModerateCritical CareSeptic shockRCPSC IM

A 63-year-old man with cirrhosis from metabolic dysfunction-associated steatohepatitis is admitted to a Winnipeg ICU with septic shock from spontaneous bacterial peritonitis. After 30 mL/kg crystalloid and ceftriaxone, mean arterial pressure remains 58 mm Hg and lactate is 5.4 mmol/L. Bedside ultrasound shows no tamponade and a collapsible inferior vena cava is no longer present. What is the most appropriate management?

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Correct answer: AStart norepinephrine and continue source-directed care

Persistent hypotension after adequate initial fluid resuscitation in septic shock requires norepinephrine as first-line vasopressor, alongside antibiotics and source control.

Reference: Surviving Sepsis Campaign; Canadian critical care practice