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Gout — RCPSC IM MCQ

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ModerateRheumatologyGoutRCPSC IM

A 64-year-old man with CKD stage 3 and recurrent podagra has six flares in the past year. Serum urate is 610 umol/L. He is asymptomatic today and takes hydrochlorothiazide and low-dose acetylsalicylic acid after a prior myocardial infarction. What is the most appropriate management?

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Correct answer: DStart low-dose allopurinol with flare prophylaxis and titrate to serum urate target

Frequent gout flares warrant urate-lowering therapy. Allopurinol can be used in CKD with low starting dose, prophylaxis against flares and treat-to-target titration.

Reference: Canadian Rheumatology Association resources; ACR gout guideline