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Buruli ulcer — DTM&H MCQ

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HardTropical bacterial infectionsBuruli ulcerDTM&H

PCR confirms a 24-cm Mycobacterium ulcerans ulcer crossing a knee joint. Which plan best reflects current WHO treatment principles?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Rifampicin plus clarithromycin with wound, surgical and rehabilitation input

The best answer is “Rifampicin plus clarithromycin with wound, surgical and rehabilitation input”. WHO recommends combination rifampicin and clarithromycin rather than surgery or monotherapy alone. A large lesion near a joint also needs wound care, assessment for debridement or grafting, physiotherapy and disability prevention. Surgery is complementary and should not displace effective antimycobacterial treatment.

Reference: WHO: Buruli ulcer: https://www.who.int/health-topics/buruli-ulcer