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Zika in pregnancy — DTM&H MCQ

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HardTropical viral infectionsZika in pregnancyDTM&H

A woman at 12 weeks’ gestation returns from a Zika-risk area after a self-limited illness with rash, conjunctivitis and arthralgia that began during travel. She is now well. In current UK practice, which investigation pathway is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BRefer through UKHSA RIPL with pregnancy and travel details and plan specialist obstetric ultrasound

The best answer is “Refer through UKHSA RIPL with pregnancy and travel details and plan specialist obstetric ultrasound”. Previous compatible symptoms after risk-area travel meet the UK indication for laboratory assessment; RIPL uses timing, geography and pregnancy information to select PCR or serology panels, while obstetric review plans ultrasound surveillance. A single private IgG result cannot safely exclude infection, amniocentesis is not the first maternal test, partner semen testing does not diagnose maternal infection, and routine antenatal care without imported-infection assessment ignores potential congenital infection despite symptom resolution.

Reference: UKHSA/GOV.UK: Zika virus sample testing advice: https://www.gov.uk/guidance/zika-virus-sample-testing-advice UKHSA/GOV.UK: Health advice for women returning from areas with Zika risk: https://www.gov.uk/guidance/health-advice-for-women-returning-from-areas-with-a-risk-of-zika-virus