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Latent tuberculosis — SCE Respiratory MCQ

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EasyRespiratory InfectionsLatent tuberculosisSCE Respiratory

A 28-year-old close contact of smear-positive pulmonary TB has a positive IGRA, normal CXR and no symptoms. She is not pregnant and baseline liver tests are normal. HIV testing is negative. What is the most appropriate management?

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Correct answer: C — Offer latent tuberculosis treatment after excluding active disease

Positive IGRA after close exposure with a normal CXR indicates latent TB once active disease has been excluded, and treatment should be offered. Four-drug therapy is for active TB. BCG vaccination does not treat latent infection and is not a substitute for chemoprophylaxis.

Reference: NICE NG33