Spontaneous bacterial peritonitis — SCE Acute Medicine MCQ
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Correct answer: C — Give intravenous antibiotics and albumin for SBP
The best answer is “Give intravenous antibiotics and albumin for SBP”. This is correct because an ascitic neutrophil count at least 250/mm3 establishes the treatment threshold. Prompt antibiotics are essential, and albumin reduces renal failure and mortality in higher-risk patients. Culture negativity is common, while drainage, diuretic escalation and albumin without antibiotics do not eradicate infection.
Reference: British Society of Gastroenterology decompensated-cirrhosis care bundle: https://www.bsg.org.uk/clinical-resource/new-decompensated-cirrhosis-admission-care-bundle