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Septic arthritis with gout crystals — SCE Rheumatology MCQ

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HardCrystal arthropathiesSeptic arthritis with gout crystalsSCE Rheumatology

A patient with gout and major cardiovascular disease cannot tolerate allopurinol. What principle governs febuxostat use?

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Correct answer: ESpecialist cardiovascular-risk review

Febuxostat is an alternative xanthine-oxidase inhibitor, but treatment selection in major cardiovascular disease requires careful review of current safety advice, alternatives and patient preference. It shares the dangerous thiopurine interaction and still requires treat-to-target monitoring.

Reference: https://www.nice.org.uk/guidance/ng219