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IgA vasculitis — SCE Rheumatology MCQ

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ModerateVasculitisIgA vasculitisSCE Rheumatology

A 33-year-old man develops palpable purpura on the legs, colicky abdominal pain and ankle arthralgia after an upper respiratory infection. Urine dip shows blood 2+ and protein 1+. Skin biopsy demonstrates leukocytoclastic vasculitis with IgA deposition. What is the most likely diagnosis?

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Correct answer: E — IgA vasculitis

Palpable purpura, arthralgia, abdominal pain and renal involvement with IgA deposition are diagnostic of IgA vasculitis. ANCA vasculitis would not show dominant IgA deposition and often has different organ involvement. Adults require careful renal follow-up because renal disease can be more severe than in children.

Reference: EULAR/PRINTO/PRES vasculitis classification; BSR rheumatology curriculum