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Hypoglycaemia from diabetes overtreatment — SCE Endocrinology MCQ

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ModerateDiabetesHypoglycaemia from diabetes overtreatmentSCE Endocrinology

A 68-year-old man with type 2 diabetes and eGFR 36 ml/min/1.73 m² has recurrent nocturnal hypoglycaemia. HbA1c is 49 mmol/mol and he lives alone after a recent fall. He takes gliclazide 160 mg twice daily and metformin 500 mg twice daily. What is the most appropriate management?

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Correct answer: ADe-intensify sulfonylurea therapy and individualise the HbA1c target

Older adults with comorbidity and hypoglycaemia need individualised targets and de-intensification of high-risk agents. Intensifying sulfonylurea therapy would increase falls and severe hypoglycaemia risk. The pearl is that overtreatment is a recognised diabetes complication.

Reference: NICE NG28, BNF