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Primary hyperparathyroidism — SCE Endocrinology MCQ

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ModerateCalcium/BonePrimary hyperparathyroidismSCE Endocrinology

A 67-year-old woman has calcium 2.92 mmol/L, phosphate 0.68 mmol/L and PTH 12.6 pmol/L. She has osteoporosis at the distal radius and two renal stones in 5 years. eGFR is 61 ml/min/1.73 m². What is the most appropriate management?

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Correct answer: ARefer for parathyroidectomy assessment

Primary hyperparathyroidism with renal stones and osteoporosis meets criteria for surgical assessment. Thiazides may worsen hypercalcaemia and are not definitive. The pearl is that target-organ involvement matters more than calcium level alone.

Reference: NICE NG132 hyperparathyroidism guideline