Mixed arterial and venous leg ulcer — SCE Dermatology MCQ
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Correct answer: E — Vascular assessment before high-compression therapy
The correct answer is E, vascular assessment before high-compression therapy. An ABPI of 0.56 with reduced toe pressures indicates significant peripheral arterial disease, and this range (0.5 to 0.8) is classically associated with a mixed arterial-venous ulcer rather than pure venous disease, even though venous eczema is present. Applying high compression in this setting risks precipitating critical limb ischaemia, tissue necrosis, or gangrene, because compression further reduces perfusion to an already compromised limb. Current UK practice mandates that any suspicion of arterial insufficiency, confirmed here by ABPI and toe pressures, triggers referral for vascular assessment (duplex, further imaging, or specialist opinion) before any high compression bandaging is started, and only reduced or modified compression under specialist supervision may later be considered if appropriate.
Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/skin-conditions