skip to main content

Post-inflammatory hyperpigmentation — SCE Dermatology MCQ

Instant feedback + full explanation. One question, done properly.

HardSkin of colourPost-inflammatory hyperpigmentationSCE Dermatology

A 16-year-old with scarring nodulocystic acne has failed adequate topical therapy and oral doxycycline. The consultant wishes to start isotretinoin. Which additional UK regulatory step applies because of age?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CObtain independent agreement from two healthcare professionals before initiation

Explanation lettering: E = shown as B · D = shown as C · B = shown as D · C = shown as E

D is correct. Current UK isotretinoin safety measures require two independent healthcare professionals to agree that no other appropriate effective treatment exists before initiation in a person under 18. This is additional to assessment and monitoring of mental health and sexual function, acknowledgement-of-risk documentation and pregnancy-prevention requirements where relevant. Isotretinoin is not prohibited in adolescents over 12 with severe resistant acne, and dose is individualized rather than automatically halved. Parental involvement does not replace valid consent or the statutory safety process.

Reference: NICE NG198: acne vulgaris management: https://www.nice.org.uk/guidance/ng198/chapter/Recommendations