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Chlamydia in pregnancy — DFSRH MCQ

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HardSTI diagnosis and managementChlamydia in pregnancyDFSRH

A 24-year-old at 9 weeks’ gestation has uncomplicated chlamydia, no pelvic pain and no macrolide allergy. Which treatment plan best matches active UK guidance?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Give azithromycin 1 g once, then 500 mg daily for 2 days

The best answer is “Give azithromycin 1 g once, then 500 mg daily for 2 days”. The active BASHH pregnancy regimen is azithromycin 1 g once followed by 500 mg daily for 2 days. Partner notification and a test of cure at least 4 weeks after treatment are also required. Doxycycline is not the routine pregnancy regimen, ceftriaxone targets gonorrhoea, and delaying treatment risks maternal and neonatal complications.

Reference: BASHH, Chlamydia guideline with active treatment updates: https://www.bashh.org/resources/15/guidelines_chlamydia_2015