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Uncomplicated gonorrhoea — DFSRH MCQ

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HardSTI diagnosis and managementUncomplicated gonorrhoeaDFSRH

A non-pregnant 25-year-old has a confirmed positive vulvovaginal gonorrhoea NAAT, no pelvic pain and a remote non-anaphylactic amoxicillin rash. Which management is most appropriate?

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Correct answer: AGive ceftriaxone 1 g IM once and arrange partner management

The best answer is “Give ceftriaxone 1 g IM once and arrange partner management”. BASHH recommends ceftriaxone 1 g intramuscularly once for confirmed uncomplicated infection. A non-severe penicillin rash does not usually preclude a third-generation cephalosporin. Doxycycline alone does not treat gonorrhoea, oral alternatives require the specified specialist regimen, and partner notification plus abstinence advice remain essential.

Reference: BASHH, Gonorrhoea Guideline 2025: https://www.bashh.org/resources/136/gonorrhoea_2025_updated_guideline/