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Hypercapnic COPD exacerbation — ABEM Board MCQ

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ModeratePulmonary emergenciesHypercapnic COPD exacerbationABEM Board

A 72-year-old woman arrives as ESI 2 with worsening shortness of breath and COPD. BP 148/82, HR 112, RR 30, SpO2 86%. VBG shows pH 7.26 and PCO2 72 mm Hg; she is awake and protecting her airway. Which of the following is the most appropriate next step in management?

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Correct answer: DStart noninvasive ventilation with bronchodilators and steroids

COPD exacerbation with hypercapnic respiratory acidosis and intact airway is an indication for noninvasive ventilation plus standard medical therapy.

Reference: GOLD COPD report; ATS/ERS NIV guidance