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Septic shock from pyelonephritis — ABEM Board MCQ

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HardInfectious disease emergenciesSeptic shock from pyelonephritisABEM Board

A 65-year-old man arrives as ESI 2 with fever, dysuria, flank pain, and confusion. BP 82/48 after 1 L crystalloid, HR 126, lactate 5.0 mmol/L, WBC 22,000/mcL, and urinalysis shows pyuria. Which of the following is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CBegin norepinephrine and broad-spectrum IV antibiotics

Septic shock after fluid resuscitation requires vasopressors and prompt broad-spectrum antibiotics.

Reference: Surviving Sepsis Campaign; IDSA complicated UTI guidance