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Carbon monoxide poisoning — ABEM Board MCQ

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EasyToxicologyCarbon monoxide poisoningABEM Board

A 28-year-old man arrives as ESI 1 after being found unconscious in a garage with a running generator. BP 118/70, HR 124, SpO2 reads 100% on pulse oximetry, and he is confused with a carboxyhemoglobin level of 28%. Which of the following is the most important immediate intervention?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdminister high-flow 100% oxygen

Pulse oximetry is unreliable in carbon monoxide poisoning; high-flow oxygen reduces carboxyhemoglobin half-life and is immediate treatment.

Reference: CDC carbon monoxide guidance; ACEP Clinical Policy: Carbon Monoxide Poisoning