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Vaccine cold-chain excursion — GPhC CRA MCQ

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ModerateDispensing and SupplyVaccine cold-chain excursionGPhC CRA

A fridge temperature log in a pharmacy shows vaccines were stored at 12C overnight for 9 hours after a door was left ajar. The stock is now back at 5C. A clinic is due to collect the vaccines in 30 minutes. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DQuarantine the vaccines and seek manufacturer or specialist stability advice

Cold-chain excursions can affect vaccine potency and require quarantine while stability advice is obtained. Returning the fridge to range does not prove the stock remains suitable. The pharmacist should document the incident and follow SOPs before any supply.

Reference: Green Book; MEP