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Penicillin allergy and sinusitis — GPhC CRA MCQ

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ModerateInfectionsPenicillin allergy and sinusitisGPhC CRA

A 40-year-old woman presents a prescription for amoxicillin 500mg three times daily despite a recorded history of immediate anaphylaxis to penicillin. She now has uncomplicated sinusitis symptoms for three days, is afebrile and has no facial swelling. What is the most appropriate alternative?

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Correct answer: C — Do not supply amoxicillin and discuss no antibiotic or a suitable alternative with the prescriber

Immediate anaphylaxis to penicillin is a major safety issue and amoxicillin should not be supplied. Acute sinusitis is commonly self-limiting, and antibiotics may not be needed early without severe features. The pharmacist should contact the prescriber and advise symptomatic care or an appropriate alternative if indicated.

Reference: NICE CKS; BNF