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Antiemetic in Parkinson's disease — GPhC CRA MCQ

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HardGI TherapeuticsAntiemetic in Parkinson's diseaseGPhC CRA

A 44-year-old man collects metoclopramide 10mg three times daily for nausea after migraine. He has Parkinson's disease treated with co-beneldopa and had dystonia with prochlorperazine previously. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Contact the prescriber for an antiemetic suitable for Parkinson's disease

Metoclopramide and prochlorperazine can worsen Parkinsonism and cause extrapyramidal effects. The previous dystonia strengthens the concern. The pharmacist should contact the prescriber for a suitable alternative rather than dispensing routinely.

Reference: BNF; NICE CKS