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Paracetamol duplication with co-codamol — GPhC CRA MCQ

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ModerateCNS TherapeuticsParacetamol duplication with co-codamolGPhC CRA

A 61-year-old man with chronic kidney disease is prescribed co-codamol 30/500 two tablets four times daily for sciatica. He already takes OTC paracetamol 1g four times daily. He has constipation and drives a forklift. What is the most appropriate action?

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Correct answer: C — Explain paracetamol duplication and refer for safer pain management

Co-codamol contains paracetamol, so the prescribed dose plus OTC paracetamol would exceed safe daily exposure. Codeine can worsen constipation and impair driving or machinery operation. The pharmacist should intervene before supply and discuss safer analgesia with the prescriber.

Reference: BNF; NICE CKS