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Dapagliflozin in heart failure — GPhC CRA MCQ

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HardCardiovascular TherapeuticsDapagliflozin in heart failureGPhC CRA

A 70-year-old woman with heart failure is prescribed dapagliflozin 10mg daily. She takes bumetanide and ramipril and has had postural dizziness during a recent heatwave. She asks what monitoring and advice are needed. What monitoring is required?

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Correct answer: C — Renal function, volume status and sick-day advice during acute illness

SGLT2 inhibitors can contribute to volume depletion, particularly with diuretics, and renal function should be considered. Sick-day advice is important because acute illness, dehydration or reduced intake can increase ketoacidosis and renal risks. Postural dizziness indicates the need for careful review rather than simple reassurance.

Reference: BNF; NICE CKS