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Warfarin INR during infection — GPhC CRA MCQ

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HardCardiovascular TherapeuticsWarfarin INR during infectionGPhC CRA

A 60-year-old woman with AF takes warfarin and has an INR target of 2.5. She starts co-amoxiclav for cellulitis and reports reduced appetite. Her INR today is 3.7 with no major bleeding. What monitoring is required?

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Correct answer: CArrange prompt INR follow-up through the anticoagulation service

Acute infection, antibiotics and reduced dietary intake can destabilise warfarin control. An INR of 3.7 without major bleeding usually requires anticoagulation service advice rather than community pharmacy dose changes alone. The pharmacist should provide bleeding safety-netting and ensure follow-up.

Reference: BNF; NICE CKS