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Opioid-induced constipation — GPhC CRA MCQ

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ModerateCNS TherapeuticsOpioid-induced constipationGPhC CRA

A 57-year-old man prescribed morphine sulfate modified-release 30mg twice daily after palliative care review also receives morphine oral solution 10mg/5mL when required. He has no laxative on the prescription and reports no bowel movement for three days. What is the most appropriate alternative?

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Correct answer: A — Add or request a stimulant laxative with an osmotic laxative if needed

Opioid-induced constipation should be anticipated and treated proactively. A stimulant laxative is commonly required, with an osmotic agent added if response is inadequate. Bulk-forming agents may worsen symptoms if fluid intake is poor or bowel motility is reduced.

Reference: BNF; NICE CKS