skip to main content

NSAID and DOAC bleeding risk — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCardiovascular TherapeuticsNSAID and DOAC bleeding riskGPhC CRA

A 59-year-old man taking rivaroxaban 20mg daily for AF asks to buy ibuprofen for dental pain. He has hypertension and a previous gastric ulcer. Paracetamol has helped only slightly. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Ibuprofen increases bleeding risk when used with rivaroxaban

NSAIDs increase bleeding risk with anticoagulants, and previous ulcer disease adds further risk. This is a clinically important OTC interaction to identify at the counter. The pharmacist should advise safer analgesia options and dental review rather than routine ibuprofen sale.

Reference: BNF; NICE CKS