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Mesalazine renal monitoring — GPhC CRA MCQ

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ModerateGI TherapeuticsMesalazine renal monitoringGPhC CRA

A 67-year-old man taking mesalazine modified-release tablets for ulcerative colitis asks why his GP has requested blood and urine tests. He is well and has had no flare for 8 months. His repeat prescription is due today. What monitoring is required?

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Correct answer: B — Renal function monitoring during mesalazine treatment

Mesalazine can rarely cause renal impairment, so renal function monitoring is required at baseline and periodically. The patient being clinically well does not remove the monitoring need. The pharmacist should reinforce adherence and advise reporting unexplained bruising, bleeding or worsening symptoms.

Reference: BNF; NICE CKS