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Suspected pulmonary embolism in pregnancy with leg symptoms — SCE Acute Medicine MCQ

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HardPublic health and women's acute medicineSuspected pulmonary embolism in pregnancy with leg symptomsSCE Acute Medicine

A 31-year-old woman at 30 weeks' gestation presents with pleuritic chest pain and dyspnoea. Oxygen saturation is 94% on air, pulse is 112/min and chest radiograph is normal. Left calf is swollen and tender. She has no bleeding risk. What is the most appropriate next step in management?

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Correct answer: EStart low-molecular-weight heparin and arrange compression ultrasound of the leg

In pregnancy with suspected PE and signs of DVT, anticoagulation with LMWH should start while objective testing is arranged, unless contraindicated. D-dimer is less useful in pregnancy and should not be used alone to discharge a symptomatic patient. Warfarin and DOACs are generally avoided for acute VTE treatment in pregnancy.

Reference: RCOG Green-top guideline 37b; NICE NG158 venous thromboembolic diseases