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Exertional rhabdomyolysis with acute kidney injury risk — SCE Acute Medicine MCQ

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ModerateRenal medicineExertional rhabdomyolysis with acute kidney injury riskSCE Acute Medicine

A 34-year-old marathon runner collapses in hot weather with muscle pain and dark urine. CK is 42,000 U/L, creatinine is 186 micromol/L and potassium is 5.4 mmol/L. He is alert after cooling and has no pulmonary oedema. What is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EGive intravenous crystalloid to maintain renal perfusion with frequent electrolyte monitoring

Exertional rhabdomyolysis with AKI risk requires intravenous fluids, monitoring of potassium, calcium, phosphate and renal function, and treatment of hyperkalaemia if it worsens. Dialysis is reserved for standard indications, not prophylaxis based on CK alone. Cooling treats heat illness but does not remove the renal risk from myoglobinuria.

Reference: NICE NG148 acute kidney injury; UK Kidney Association AKI guidance