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Adrenal crisis — SCE Acute Medicine MCQ

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ModerateAcute Renal and Metabolic EmergenciesAdrenal crisisSCE Acute Medicine

A 42-year-old man with known Addison's disease presents with vomiting, abdominal pain and collapse after influenza-like illness. Blood pressure is 78/44 mmHg, sodium 126 mmol/L, potassium 5.9 mmol/L and glucose 3.4 mmol/L. What is the most important immediate action?

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Reveal the answer and explanation

Correct answer: DGive intramuscular or intravenous hydrocortisone immediately

Adrenal crisis is a clinical emergency and hydrocortisone should be given immediately, with fluids and glucose as needed. Treatment should not wait for cortisol results when the presentation is classic. Fludrocortisone alone does not provide adequate acute glucocorticoid effect. The pearl is that steroid replacement is time-critical and should precede diagnostic neatness.

Reference: Society for Endocrinology adrenal crisis guidance