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Diabetic ketoacidosis — SCE Acute Medicine MCQ

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ModerateAcute Renal and Metabolic EmergenciesDiabetic ketoacidosisSCE Acute Medicine

A 28-year-old woman with type 1 diabetes presents with vomiting and abdominal pain. Glucose is 28 mmol/L, capillary ketones are 6.2 mmol/L, venous pH is 7.12 and potassium is 4.9 mmol/L. She has missed basal insulin for two days. What is the most appropriate next step in management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: DStart fixed-rate intravenous insulin and 0.9% sodium chloride

This is DKA, requiring fixed-rate IV insulin, fluid resuscitation and potassium-guided replacement. Glucose-containing fluid is added later when glucose falls, not as initial resuscitation unless clinically indicated. Bicarbonate is not routine and does not address ketogenesis. The pearl is that resolution is judged by ketone clearance and acidosis, not glucose alone.

Reference: JBDS DKA guideline 2023