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Isotretinoin psychiatric adverse effects — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyIsotretinoin psychiatric adverse effectsGPhC CRA

A patient taking isotretinoin reports low mood and thoughts that life is not worth living. She is halfway through treatment and has a dermatology appointment in 6 weeks. What is the most appropriate action?

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Correct answer: D — Arrange urgent mental-health assessment and contact the prescriber

Mood change and suicidal thoughts during isotretinoin therapy require urgent assessment. The pharmacist should take the concern seriously, ensure immediate safety support and contact the prescriber. A Yellow Card report may also be appropriate for suspected serious adverse effects.

Reference: BNF; MHRA Drug Safety Update